Neuromodulatros VS Fillers: WHAT’S THE DIFFERENCE?

If you’re exploring non-surgical anti-aging treatments, chances are you’ve come across the terms neuromodulators and dermal fillers. Both are popular injectable aesthetic treatments
used to reduce wrinkles and restore youthful volume but they work in entirely different ways.

At Très Jolie Medical Spa, we specialize in customized facial rejuvenation using both neuromodulators (like Botox, Dysport) and dermal fillers (like Juvéderm, Restylane, Sculptra and Radiesse). Understanding the difference between the two can help you make the best decision for your beauty goals.

What Are Neuromodulators?

Neuromodulators are injectable treatments made from botulinum toxin type A, a purified protein that temporarily relaxes facial muscles. Brand names include:

  • Botox®
  • Dysport®
  • Xeomin®
  • Jeuveau®

How Neuromodulators Work

Neuromodulators block nerve signals that cause muscle contractions. By relaxing specific facial muscles, they soften dynamic wrinkles the lines formed by facial expressions like frowning, squinting, and smiling.

Common Areas Treated with Neuromodulators

  • Forehead lines
  • Frown lines (a.k.a. “11s” between the brows)
  • Crow’s feet (outer corners of the eyes)
  • Bunny lines (on the nose)
  • Jawline (for slimming or TMJ relief)
  • Neck bands (platysmal bands)

Neuromodulator Results & Longevity

  • Visible results: 3–7 days
  • Full effect: Around 2 weeks
  • Duration: 3–4 months
  • Downtime: Minimal to none

What Are Dermal Fillers?

Dermal fillers are injectable gels designed to restore volume, contour the face, and smooth static wrinkles. Most fillers contain hyaluronic acid (HA), a moisture-binding molecule naturally found in your skin. Others include:

  • Calcium hydroxylapatite (e.g., Radiesse®)
  • Poly-L-lactic acid (e.g., Sculptra®)

How Dermal Fillers Work

Unlike neuromodulators, fillers don’t affect muscles. Instead, they “fill in” areas of volume loss or are used to enhance features like the cheeks, lips, and jawline.

Common Areas Treated with Dermal Fillers

  • Cheeks (for lift and volume)
  • Lips (for shape, volume, and hydration)
  • Nasolabial folds (smile lines)
  • Marionette lines (lines from mouth corners downward)
  • Under-eye hollows
  • Jawline and chin (for sculpting)
  • Hands (to restore volume and smoothness)

Dermal Filler Results & Longevity

  • Visible results: Immediately
  • Duration: 6 months to 2+ years (depending on product & area)
  • Downtime: Mild swelling or bruising possible

Can You Combine Botox and Fillers?

Yes, absolutely! Combining neuromodulators and dermal fillers offers comprehensive facial rejuvenation, often referred to as a liquid facelift.

For example:

  • Botox® smooths forehead lines and crow’s feet
  • Juvéderm, Restylane, Radiesse restores cheek volume or sculpts the jawline

Together, they can help you look refreshed, lifted, and more youthful without surgery or downtime.

Why Choose Très Jolie Medical Spa?

At Très Jolie Medical Spa, we pride ourselves on expert-level facial artistry and custom treatment plans tailored to your unique anatomy and goals. Our providers are mastered trained in advanced injection techniques, ensuring natural-looking, beautiful results every time.

Whether you’re new to injectables or looking to refresh your current routine, we’re here to guide you every step of the way.

Ready to Transform Your Look?

Book a free consultation with one of our expert injectors today and discover the perfect treatment plan for your skin, face, and lifestyle.

🔗 Schedule Your Appointment Now
📍 Located in Lake Mary, FL | Serving Central Florida

 

More Questions? We’ve Got You Covered:

  • Is Botox better than fillers?
  • How long do dermal fillers last?
  • What is the best filler for lips or under-eyes?
  • Can I do Botox and fillers on the same day?

Visit our Injectables FAQ page or contact us directly at 407-915-6570 or [email protected]

Chloe Leskanic

Fitness Instructor / CoolSculpting Specialist

Chloe Leskanic is a dedicated Patient Coordinator and skilled CoolSculpting provider, known for her commitment to delivering exceptional sculpting results. Trained by a double master sculpting expert, Chloe possesses a deep understanding of the nuances involved in body contouring. Her passion for superior sculpting outcomes drives her to stay updated with the latest techniques and advancements in the field.

With a warm and approachable demeanor, Chloe ensures that every patient’s journey is personalized and comfortable, guiding them through the process with expertise and care. Her attention to detail and dedication to patient satisfaction make her a trusted partner in achieving aesthetic goals. Whether you’re looking to enhance your natural silhouette or explore the transformative effects of CoolSculpting, Chloe is here to help you every step of the way.

Kimberly Buitron

Licensed Medical Aesthetician Anti-Aging Specialist
As a passionate and skilled Medical Aesthetician, Kimberly specializes in delivering advanced skincare treatments that enhance her clients’ natural beauty and help them achieve their aesthetic goals. With a deep understanding of skin anatomy, the latest skincare technologies, and an eye for detail, Kimberly provides customized treatments that address a wide variety of skin concerns, including aging, acne, hyperpigmentation, and more. Book your anti-aging facial or consultation with Kimberly today! 

Deanna Vazquez

ARNP / Board Certified Injector
Deanna R Vazquez, ARNP, MSN, FNP-BC is a master’s prepared nurse practitioner, ANCC Board Certified in Family Practice. She is trained and industry certified in cosmeceutical procedures such as neuromodulators, dermal fillers, lipolysis injections, minimally invasive laser, and PDO thread lift.

Deanna joined Tres Jolie Medical Spa in 2018. She has over 15 years of medical experience and over 7 years in aesthetics. She received her Master of Nursing from South University in Orlando as a nurse practitioner with special studies in family medicine. Her professional memberships include the Florida Nurse Practitioner association.

Deanna provides education in a professional and confidential manner offering her clients the highest level of assurance and trust. She has extensive training with Susan Leskanic and participates in the latest cutting edge aesthetic medicine. She is highly qualified, educated, confident and experienced in aesthetic procedures and is committed to helping each client achieve their individual goals. Just as every face is unique, so is every injector and every practice. She is committed to us and will be committed to you. Most people get their hair cut or teeth cleaned by the same person every time. You will have the same injector at Tres Jolie.

Chandler Leskanic

PA. Physician Assistant/Board Certified Injector

Chandler Leskanic is a Master Injector and board certified Physician Associate, known for her exceptional ability to create beautiful, natural results in aesthetic treatments. With a passion for enhancing individual beauty, Chandler has trained under a triple master injector, mastering the latest techniques in cosmetic injectables and laser treatments .
Her keen eye for detail and commitment to patient satisfaction set her apart in the field. Chandler believes that every client deserves a personalized approach, ensuring that each treatment complements their unique features and enhances their natural beauty.
With a focus on safety, artistry, and transformative results, Chandler is dedicated to helping clients feel confident and radiant in their own skin. Whether it’s subtle enhancements or more significant transformations, she is committed to delivering results that exceed expectations.