Semaglutide & Tirzepatide Weight-Loss
Semaglutide & Tirzepatide Weight-Loss
At Très jolie Medical Spa, we offer medically supervised weight-loss programs using the latest prescription therapies: Semaglutide and Tirzepatide. These medications, when combined with personalized nutrition coaching and activity plans, have produced significant, clinically proven weight loss for many patients. All treatments are provided under the supervision of our licensed medical team with careful screening and follow-up.
How these medications work
Both semaglutide and tirzepatide are injectable medications given once weekly that help with weight loss primarily by reducing appetite and increasing feelings of fullness.
Semaglutide
Semaglutide is an FDA-approved injectable medication that mimics a natural hormone involved in appetite regulation. Originally developed for diabetes, it is now acclaimed as an effective medical weight loss option. Semaglutide helps reduce appetite, increase fullness, and support healthy weight management for those with excess weight or obesity.
Tirzepatide
Tirzepatide is a next-generation weekly injectable designed for adults with obesity, overweight, or related health concerns. It works by acting on two naturally occurring hormones to regulate appetite, reduce food intake, and support healthy metabolic function. Tirzepatide is clinically proven to support more enhanced weight loss when combined with healthy lifestyle changes.
What's the difference: Semaglutide vs Tirzepatide
Efficacy
Clinical trials show semaglutide (high-dose weekly formulations for obesity) typically produce substantial mean weight loss (often ~15% in many trials), while tirzepatide has produced larger average reductions in several large trials (approaching ~20% or more at higher doses in obesity trials). Individual results vary.
Mechanism
Semaglutide targets GLP-1. Tirzepatide targets both GIP and GLP-1, which likely explains its stronger effects in some studies.
Possible side effects
Side effects may include: nausea, vomiting, diarrhea, constipation, abdominal pain, and fatigue. These are usually most pronounced during dose escalation and often improve over time. FDA Access Data+1
Your Experience at Très Jolie Medical Spa
- Customized consultation to review health history and set personalized goals.
- Medical Nurse Practitioner / Physician Associate-guided treatment plans tailored to your needs and wellness journey.
- Comfortable environment with regular follow-ups and support for best results.
- Expert aftercare and education to maximize your success and confidence.
Is Medical Weight Loss Right For You?
Medical weight loss with Semaglutide or Tirzepatide may be ideal for adults struggling with excess weight, obesity, or weight-related health challenges. Best results occur alongside balanced nutrition and an active lifestyle, with ongoing professional support.
Safety & possible side effects
Side effects may include: nausea, vomiting, diarrhea, constipation, abdominal pain, and fatigue. These are usually most pronounced during dose escalation and often improve over time. FDA Access Data+1
Serious safety notes: Both drug classes carry boxed warnings about a potential risk of thyroid C-cell tumors (observed in rodents). They are contraindicated in patients with a personal or family history of medullary thyroid carcinoma or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Discuss your full family history with our clinicians. FDA Access Data+1
Other cautions: If you have type 2 diabetes and are on insulin or sulfonylureas, there is increased risk of hypoglycemia — dose adjustments of your diabetes medications may be needed. Pregnancy/breastfeeding — these medications are not recommended; effective contraception is advised while on treatment.
